Research Fellow at Mayo Clinic

I am interested in understanding autoimmune diseases (e.g., rheumatoid arthritis, vasculitis) from large-scale omics datasets and clinical data; and designing applications from such data for unmet clinical needs. To reach my goal, I am utilizing network-based methodologies and developing new in silico tools. Currently, I am working on a project involving a comprehensive multi-omics analysis aiming to understand the differences between different RA subtypes (i.e., ACPA-positive, ACPA-negative) and to identify diagnostic biomarkers for ACPA-negative RA patients.

Education

Ph.D. in Bioinformatics

2012 - 2019
Interdisciplinary in Bioinformatics, Seoul National University, Republic of Korea

BS in Mechanical Engineering

2007 - 2012
Hongik University, Republic of Korea

Talk & Presentation

Integrative Multi-omic Phenotyping in Blood Identifies Molecular Signatures and Candidate Biomarkers of ACPA-negative Rheumatoid Arthritis

2022
Biomedical Engineering Society 2022: Oral presentation [scheduled]

OCTOBER 12-15, SAN ANTONIO, TX

Global Transcriptomic Profiling Identifies Differential Gene Expression Signatures Between Inflammatory and Non-inflammatory Aortic Aneurysms

2022
Mayo Clinic Young Investigators Research Symposium: Oral presentation

MAY 21 (Virtual)

Global Transcriptomic Profiling Identifies Differential Gene Expression Signatures Between Inflammatory and Non-inflammatory Aortic Aneurysms

2022
International Vasculitis and ANCA workshop: Poster Presentation

APRIL 3–6 (Virtual)

Global Transcriptomic Profiling Identifies Differential Gene Expression Signatures Between Inflammatory and Non-inflammatory Aortic Aneurysms

2021
American College of Rheumatology Convergence 2021: Oral presentation

NOVEMBER 6 (Virtual)

Plasma Metabolomic Features Predictive of Disease Activity in Patients with Rheumatoid Arthritis

2021
Biomedical Engineering Society 2021: Oral presentation

OCTOBER 6–9, Orlando, FL

Bioinformatics at Clinic

2021
Chungbuk National University: Seminar at Dr. Jo Lab

AUGUST 17 (Virtual)

Recent Publications

Global Transcriptomic Profiling Identifies Differential Gene Expression Signatures between Inflammatory and Non‐inflammatory Aortic Aneurysms
Benjamin Hur, Matthew J Koster, Jin Sung Jang, Cornelia M Weyand, Kenneth J Warrington, Jaeyun Sung
Arthritis & Rheumatology
Adenosine A2A receptor blockade prevents cisplatin-induced impairments in neurogenesis and cognitive function
Alfredo Oliveros, Ki Hyun Yoo, Mohammad Abdur Rashid, Ana Corujo-Ramirez, Benjamin Hur, Jaeyun Sung, Yuanhang Liu, John R Hawse, Doo-Sup Choi, Detlev Boison, Mi-Hyeon Jang
Proceedings of the National Academy of Sciences
Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis
Vinod K Gupta, Kevin Y Cunningham, Benjamin Hur, Utpal Bakshi, Harvey Huang, Kenneth J Warrington, Veena Taneja, Elena Myasoedova, John M Davis, Jaeyun Sung
Genome medicine
Plasma metabolomic profiling in patients with rheumatoid arthritis identifies biochemical features predictive of quantitative disease activity
Benjamin Hur, Vinod K Gupta, Harvey Huang, Kerry A Wright, Kenneth J Warrington, Veena Taneja, John M Davis, Jaeyun Sung
Arthritis research & therapy
Venn-diaNet : Venn diagram based network propagation analysis framework for comparing multiple biological experiments
Benjamin Hur, Dongwon Kang, Sangseon Lee, Ji Hwan Moon, Gung Lee, and Sun Kim
(GIW2019 Accepted) BMC Bioinformatics
CLIP-GENE: a web service of the condition specific context-laid integrative analysis for gene prioritization in mouse TF KO experiments
Benjamin Hur, Sangsoo Lim, Heejoon Chae, Seokjun Seo, Sunwon Lee, Jaewoo Kang and Sun Kim
Biology Direct 2017, https://doi.org/10.1186/s13062-016-0158-x
Protein interaction network (PIN)-based breast cancer subsystem identification and activation measurement for prognostic modeling
S Lim, Y Park, B Hur, M Kim, W Han, S Kim
Methods 2016, https://doi.org/10.1016/j.ymeth.2016.06.015
Information theoretic sub-network mining characterizes breast cancer subtypes in terms of cancer core mechanisms
J Park, B Hur, S Rhee, S Lim, M Kim, K Kim, W Han and S Kim
Journal of Bioinformatics and Computational Biology, 2016 https://doi.org/10.1142/S0219720016440029
RDDpred: a condition-specific RNA-editing prediction model from RNA-seq data.
Min-su Kim, Benjamin Hur and Sun Kim
BMC Genomics, 2016 https://doi.org/10.1186/s12864-015-2301-y
Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.
Bu-NamJeon, Jae-HyeonYoona, Min-KyeongKim, Won-Il Choi, Dong-InKoh, Benjamin Hur, Kunhong Kim, Kyung-Sup Kim, and Man-Wook Hur
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2016, https://doi.org/10.1016/j.bbagrm.2016.09.004
Combined analysis for GRN and SNV information enhances identification of potential gene markers in mouse knockout studies with small number of samples.
Benjamin Hur, Heejoon Chae, and Sun Kim
BMC Medical Genomics 2015, https://dx.doi.org/10.1186%2F1755-8794-8-S2-S10